Alle Jahre wieder müssen/dürfen/können die Studierenden der Bioinformatik im Wahlpflichtmodul „Current Bioinformatics“ an der TH Bingen einen Vortrag über einen aktuellen Fachartikel halten. Der Schwerpunkt des Vortrags liegt dabei auf einem im Artikel verwendeten bioinformatischen Tool, die biologische und/oder medizinische Fragestellung des Artikels dient dabei als Anwendung. Anfänglich, also vor ca. 10 Jahren, hatte ich noch Mühe, geeignete Artikel zu finden. Inzwischen kann ich aus dem Vollen schöpfen und weiß selbst nicht, welchen Artikel ich am Interessantesten finde. Außerdem habe ich sicher noch etliches verpasst oder vergessen …

• A comprehensive genomic history of extinct and living elephants, Eleftheria Palkopoulou, Mark Lipson, Swapan Mallick, Svend Nielsen, Nadin Rohland, Sina Baleka, Emil Karpinski, Atma M. Ivancevic, Thu-Hien To, R. Daniel Kortschak, Joy M. Raison, Zhipeng Qu, Tat-Jun Chin, Kurt W. Alt, Stefan Claesson, Love Dalén, Ross D. E. MacPhee, Harald Meller, Alfred L. Roca, Oliver A. Ryder, David Heiman, Sarah Young, Matthew Breen, Christina Williams, Bronwen L. Aken, Magali Ruffier, Elinor Karlsson, Jeremy Johnson, Federica Di Palma, Jessica Alfoldi, David L. Adelson, Thomas Mailund, Kasper Munch, Kerstin Lindblad-Toh, Michael Hofreiter, Hendrik Poinar and David Reich, PNAS (2018)
• 8.2% of the Human Genome Is Constrained: Variation in Rates of Turnover across Functional Element Classes in the Human Lineage, Chris M. Rands, Stephen Meader, Chris P. Ponting, Gerton Lunter, PLoS Genet (2014) 10 (7): e1004525
• Eukaryotic association module in phage WO genomes from Wolbachia, Bordenstein, S. R. & Bordenstein, S. R., Nat. Commun. (2016) 7, 13155
• First nuclear genome assembly of an extinct moa species, the little bush moa (Anomalopteryx didiformis), Alison Cloutier, Timothy B. Sackton, Phil Grayson, Scott V. Edwards, Allan J. Baker, bioRxiv (2018) 262816
• Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of Bacterial Plasmids Conferring Carbapenem Resistance, Rebecca A. Weingarten, Ryan C. Johnson, Sean Conlan, Amanda M. Ramsburg, John P. Dekker, Anna F. Lau, Pavel Khil, Robin T. Odom, Clay Deming, Morgan Park, Pamela J. Thomas, NISC Comparative Sequencing Program, David K. Henderson, Tara N. Palmore, Julia A. Segre, Karen M. Frank,
  mbio (2018) vol. 9 no. 1 e02011-17
• Genomics of the origin and evolution of Citrus, Guohong Albert Wu, Javier Terol, Victoria Ibanez, Antonio López-García, Estela Pérez-Román, Carles Borredá, Concha Domingo, Francisco R. Tadeo, Jose Carbonell-Caballero, Roberto Alonso, Franck Curk, Dongliang Du, Patrick Ollitrault, Mikeal L. Roose, Joaquin Dopazo, Frederick G. Gmitter, Daniel S. Rokhsar and Manuel Talon, Nature (2018) 554, pages 311–316
• Insular Celtic population structure and genomic footprints of migration, Ross P. Byrne, Rui Martiniano, Lara M. Cassidy, Matthew Carrigan, Garrett Hellenthal, Orla Hardiman, Daniel G. Bradley, Russell L. McLaughlin, PLoS Genet (2018) 14(1): e1007152
• Large-scale genetic census of an elusive carnivore, the European wildcat (Felis s. silvestris), Katharina Steyer, Robert H. S. Kraus, Thomas Mölich, Ole Anders, Berardino Cocchiararo, Christiane Frosch, Alexander Geib, Malte Götz, Mathias Herrmann, Karsten Hupe, Annette Kohnen, Matthias Krüger, Franz Müller, Jacques B. Pir, Tobias E. Reiners, Susan Roch, Ulrike Schade, Philipp Schiefenhövel, Mascha Siemund, Olaf Simon, Sandra Steeb, Sabrina Streif, Bruno Streit, Jürgen Thein, Annika Tiesmeyer, Manfred Trinzen, Burkhard Vogel, Carsten Nowak, Conserv Genet (2016) 17: 1183
• Little evidence for enhanced phenotypic evolution in early teleosts relative to their living fossil sister group, John T. Clarke, Graeme T. Lloyd, Matt Friedman, PNAS (2016) 113 (41) 11531-11535
• Massive horizontal transfer of transposable elements in insects, Jean Peccoud, Vincent Loiseau, Richard Cordaux, Clément Gilbert, PNAS (2017) 114 (18) 4721-4726
• Multi-locus Analyses Reveal Four Giraffe Species Instead of One, Julian Fennessy, Tobias Bidon, Friederike Reuss, Vikas Kumar, Paul Elkan, Maria A. Nilsson, Melita Vamberger, Uwe Fritz, Axel Janke, Current Biology (2016) Volume 26, Issue 18, 2543-2549
• New species from Ethiopia further expands Middle Pliocene hominin diversity, Yohannes Haile-Selassie, Luis Gibert, Stephanie M. Melillo, Timothy M. Ryan, Mulugeta Alene, Alan Deino, Naomi E. Levin, Gary Scott, Beverly Z. Saylor, Nature (2015) 521, pages 483–488
• Sheep genome functional annotation reveals proximal regulatory elements contributed to the evolution of modern breeds, Marina Naval-Sanchez, Quan Nguyen, Sean McWilliam, Laercio R. Porto-Neto, Ross Tellam, Tony Vuocolo, Antonio Reverter, Miguel Perez-Enciso, Rudiger Brauning, Shannon Clarke, Alan McCulloch, Wahid Zamani, Saeid Naderi, Hamid Reza Rezaei, Francois Pompanon, Pierre Taberlet, Kim C. Worley, Richard A. Gibbs, Donna M. Muzny, Shalini N. Jhangiani, Noelle Cockett, Hans Daetwyler, James Kijas, Nature Communications (2018) volume 9, Article number: 859
• Single sample resolution of rare microbial dark matter in a marine invertebrate metagenome, Ian J. Miller, Theodore R. Weyna, Stephen S. Fong, Grace E. Lim-Fong, Jason C. Kwan, Sci. Rep. (2016) 6, 34362
• Singleton Variants Dominate the Genetic Architecture of Human Gene Expression, Ryan D. Hernandez, Lawrence H. Uricchio, Kevin Hartman, Jimmie Ye, Andrew Dahl, Noah Zaitlen, bioRxiv (2017) 219238
• Strains, functions and dynamics in the expanded Human Microbiome Project, Jason Lloyd-Price, Anup Mahurkar, Gholamali Rahnavard, Jonathan Crabtree, Joshua Orvis, A. Brantley Hall, Arthur Brady, Heather H. Creasy, Carrie McCracken, Michelle G. Giglio, Daniel McDonald, Eric A. Franzosa, Rob Knight, Owen White, Curtis Huttenhower, Nature (2017) volume 550, pages 61–66
• Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere Jônatas Abrahão, Lorena Silva, Ludmila Santos Silva, Jacques Yaacoub Bou Khalil, Rodrigo Rodrigues, Thalita Arantes, Felipe Assis, Paulo Boratto, Miguel Andrade, Erna Geessien Kroon, Bergmann Ribeiro, Ivan Bergier, Herve Seligmann, Eric Ghigo, Philippe Colson, Anthony Levasseur, Guido Kroemer, Didier Raoult, Bernard La Scola, Nature Communications (2018) volume 9, Article number: 749
• The sponge microbiome project, Lucas Moitinho-Silva, Shaun Nielsen, Amnon Amir, Antonio Gonzalez, Gail L. Ackermann, Carlo Cerrano, Carmen Astudillo-Garcia, Cole Easson, Detmer Sipkema, Fang Liu, Georg Steinert, Giorgos Kotoulas, Grace P. McCormack, Guofang Feng, James J. Bell, Jan Vicente, Johannes R. Björk, Jose M. Montoya, Julie B. Olson, Julie Reveillaud, Laura Steindler, Mari-Carmen Pineda, Maria V. Marra, Micha Ilan, Michael W. Taylor, Paraskevi Polymenakou, Patrick M. Erwin, Peter J. Schupp, Rachel L. Simister, Rob Knight, Robert W. Thacker, Rodrigo Costa, Russell T. Hill, Susanna Lopez-Legentil, Thanos Dailianis, Timothy Ravasi, Ute Hentschel, Zhiyong Li, Nicole S. Webster, Torsten Thomas, GigaScience (2017) Volume 6, Issue 10, Pages 1–7
• Transmission between Archaic and Modern Human Ancestors during the Evolution of the Oncogenic Human Papillomavirus 16, Ville N. Pimenoff, Cristina Mendes de Oliveira, Ignacio G. Bravo, Molecular Biology and Evolution (2017) Volume 34, Issue 1, Pages 4–19
• Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection, Emanuel Wyler, Jennifer Menegatti, Vedran Franke, Christine Kocks Anastasiya Boltengagen, Thomas Hennig, Kathrin Theil, Andrzej Rutkowski, Carmelo Ferrai, Laura Baer, Lisa Kermas, Caroline Friedel, Nikolaus Rajewsky, Altuna Akalin, Lars Dölken, Friedrich Grässer, Markus Landthaler, Genome Biology (2017) 18:209
• Assembly of 913 microbial genomes from metagenomic sequencing of the cow rumen Robert D. Stewart, Marc D. Auffret, Amanda Warr, Andrew H. Wiser, Maximilian O. Press, Kyle W. Langford, Ivan Liachko, Timothy J. Snelling, Richard J. Dewhurst, Alan W. Walker, Rainer Roehe & Mick Watson, Nature Communications (2018) volume 9, Article number: 870